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Specification Sheet

BIIB 021, ≥98%

: 6-Chloro-9-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-9H-purin-2-amine

: B 8637

: C14H15ClN6O

: 318.76

: BIIB 021 binds in the ATP-binding pocket of Hsp90, interferes with Hsp90 chaperone function, and results in client protein degradation and tumor growth inhibition.

: B 8637 BIIB 021, ≥98% - a novel inhibitor of Hsp90


Properties

: Solid

: White

: ≥98%

: Store at -20°C

: Soluble to 100 mM in DMSO


Safety Information

Dangerous Goods Info: NA
References: Lundgren, K. et al.: Mol. Cancer Ther., 8, 921 (2009); Boell, B. et al.: Clin. Cancer Res., 15, 5108 (2009); Yin, X. et al.: Int. J. Cancer, 126, 1216 (2010);


PackingsPrice (INR)
5 mg 39906.00
10 mg 58509.00