SB 431542 is a small molecule that acts as a specific and selective inhibitor of TGFβ RI, ACTR-IB and ACTR-IC (transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors ALK4, 5, and 7).
S 0619 (OTTO) SB 431542 hydrate ≥98% (HPLC), powder Cas 301836-41-9 - used to study the correlation of platelet-derived growth factor receptor B expression and TGF-β pathway activation in colorectal tumor cells. S 0619 (OTTO) SB 431542 hydrate ≥98% (HPLC), powder Cas 301836-41-9 - used to study the role of TGF-β signaling in modulation of extracellular matrix and myoblast differentiation.