H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) non competitively inhibits the action of nitric oxide-sensitive guanylyl cyclase and results in a supposedly irreversible oxidation of the prosthetic heme group.
O 0646 (OTTO) 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one Cas no 41443-28-1 - used to study the role of cyclic guanosine monophosphate (cGMP) pathway in nitric oxide (NO) signal transduction.