HATU (1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate, Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid.
H 1218 (OTTO) HATU, 99% Cas 148893-10-1 - used along with Hünig's base (N,N-diisopropylethylamine, DIPEA) to form amide bonds. H 1218 (OTTO) HATU, 99% Cas 148893-10-1 - used as an additive in peptide synthesis., It is also involved efficiently to speed up the coupling process and reduces the loss of chiral integrity.