n-Hydroxysuccinimide (NHS) is an organic compound with the formula C4H5NO3. Being slightly acidic, it is an irritant to skin, eyes and mucous membranes.
H 0168 (OTTO) n-Hydroxy succinimide, 99% Cas no 6066-82-6 - used in the activation of carboxylic acids to NHS-esters to promote coupling with nucleophiles. This approach is most commonly employed in activating the free acid forms of fluorophores for promoting conjugation of these fluorophores to amine residues of proteins.