C 2259 (OTTO) Chromium picolinate Cas 14639-25-9 - used to study its effects on nuclear factor-κ B (NF-κB) and nuclear factor-E2-related factor-2 (Nrf2) pathways in animals. C 2259 (OTTO) Chromium picolinate Cas 14639-25-9 - used to study its potential as a modulator of glucose uptake and the activity of insulin.