Carbonyldiimidazole, 98%

Description

1,1'-Carbonyldiimidazole (CDI) is an organic compound with the molecular formula (C3H3N2)2CO. It is a white crystalline solid.

Application

C 1626a (OTTO) Carbonyldiimidazole, 98% Cas 530-62-1 - used for esterification, although alcoholysis requires heat or the presence of a potent nucleophiles as sodium ethoxide, and other strong bases like NaH. This reaction has generally good yield and wide scope (though forming the ester from tertiary alcohols when the acid reagent has a relatively acidic α-proton is troublesome, since C-C condensations can occur, though this itself may be a desirable reaction).A similar reaction involving thiols and selenols can yield the corresponding esters.The alcohol reaction can be used to form glycosidic bonds, as well.