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Camptothecin
C 0778
puriss
C20H16N2O4
7689-03-4
90%
348.35
C 0778 (OTTO) (S)-(+)-Camptothecin, 90% Cas 7689-03-4 - used this knowledge to unearth new mechanisms of action for inhibiting cancer cell growth
Camptothecin was originally isolated from the stem wood of the Camptotheca acuminata tree and was shown to exhibit antileukemic/antitumor activity, and reversibly inhibit Mitochondrial Topo I (nuclear Topo I (topoisomerase I)) by binding to and stabilizing the topoisomerase-DNA covalent complex.
Antibiotics
Powder
260 °C (dec.)(lit.)
2-8 °C
RIDADR UN 1544PSN1 6.1 / PGIIIWGK Germany 3
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